Part 1: Renal Physiology 1

Chapter 1: Introduction to Renal Function 3
Chapter 2: Renal Circulation and Glomerular Filtration Rate 21
Chapter 3: Proximal Tubule 71
Chapter 4: Loop of Henle and the Countercurrent Mechanisms 112
Chapter 5: Functions of the Distal Nephron143
Chapter 6: Effects of Hormones on Renal Function 163

Part 2: Regulation of Water and Electrolyte Balance  239

Chapter 7: Total Body Water and the Plasma Sodium Concentration 241
Chapter 8: Regulation of the Effective Circulating Volume 258
Chapter 9: Regulation of Plasma Osmolality 285
Chapter 10: Acid-Base Physiology 299
Chapter 11: Regulation of Acid Base Balance 325
Chapter 12: Potassium Homeostasis 372

Part 3: Physiologic Approach to Acid-Base and Electrolyte Disorders 403

Chapter 13: Meaning and Application of Urine Chemistries 405
Chapter 14: Hypovolemic States 415
Chapter 15: Clinical Use of Diuretics 447
Chapter 16: Edematous States 478
Chapter 17: Introduction to Simple and Mixed Acid Base Disorders 535
Chapter 18: Metabolic Alkalosis 551
Chapter 19: Metabolic Acidosis 578
Chapter 20: Respiratory Acidosis 647
Chapter 21: Respiratory Alkalosis 673
Chapter 22: Introduction to Disorders of Osmolality 682
Chapter 23: Hypoosmolal States – Hyponatremia 696
Chapter 24: Hyperosmolal States – Hypernatremia 746
Chapter 25: Hyperosmolal States – Hyperglycemia 794
Chapter 26: Introduction to Disorders of Potassium Balance 822
Chapter 27: Hypokalemia 836
Chapter 28: Hyperkalemia 888
Chapter 29: Answers to the Problems 931
Chapter 30: Summary of Equations and Formulas 956

Index: 961